The aflatoxin pathway regulator AflR induces gene transcription inside and outside of the aflatoxin biosynthetic cluster
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چکیده
منابع مشابه
Aflatoxin Biosynthetic Pathway Enzymes
Five strains ofAspergillusfJavus lacking the ability to produce aflatoxins were examined in greenhouse tests for the ability to prevent a toxigenic strain from contaminating developing cottonseed with aflatoxins. All atoxigenic strains reduced contamination when inoculated into developing bolls 24 h prior to the toxigenic strain. However, only one strain, AF36, was highly effective when inocula...
متن کاملCharacterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster.
Production of carcinogenic aflatoxins has been reported from members of Aspergillus section Flavi, Aspergillus section Nidulantes and a newly proposed Aspergillus section Ochraceorosei that consists of Aspergillus ochraceoroseus and A. rambellii. Unlike members of section Flavi, A. ochraceoroseus and A. rambellii have been shown to accumulate both aflatoxin (AF) and the aflatoxin precursor ster...
متن کاملAflatoxin Biosynthetic Pathway and Pathway Genes
Among the over 185 known species within the genus Aspergillus, Aspergillus flavus is the most economically important because it produces the toxic and carcinogenic aflatoxins. Its non-aflatoxigenic relative A. oryzae is used extensively for food fermentations (Jelinek et al., 1989). It is one of the most abundant soil-borne molds on earth. A. flavus fungus is a saprobe mold that is capable of s...
متن کاملProgress toward a biosynthetic rationale of the aflatoxin pathway
Specifical ly—labeled samples of averufin have been synthesized and incorporated intact into aflatoxin B1, versicolorin A and versiconal acetate as determined by NMR spectroscopy. [1—'3C]--Hexanoic acid has been shown to be uti I ized as the primer of the pathway whi le a group of alternative starters was found to be degraded to acetate prior to incorporation. The correct structure of nidurufin...
متن کاملEffects of thiamine on growth, aflatoxin production, and aflr gene expression in A. parasiticus
Background and Purpose: Mycotoxins are secondary fungal metabolites with a very high diversity that are produced by some species of Aspergillus which frequently leads to contaminate food and agricultural products. Recently, elimination of aflatoxin contamination in food and feed has been considered by scientists worldwide. Although, the antibacterial and antifungal effects of vitamins as natura...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2006
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.2005.00084.x